★★★★★ (136 Reviews)

Nutrition Designed for Women

EndoBase — Daily Antioxidant + Nutrient Formula

Formulated by a clinical dietitian for women with higher nutritional demands. EndoBase combines Advanced antioxidants and nutrients to support a healthy inflammatory response, antioxidant defenses, and everyday nutritional needs.*

Supports a healthy inflammatory response*
Supports reproductive health*
Supports cellular antioxidant defenses*
Helps protect cells from oxidative stress*

Benefits

Targeted daily support, built around antioxidants.

  • EndoBase brings together NAC, quercetin, curcumin, resveratrol, methylfolate, and molybdenum in one daily formula.
  • NAC helps replenish glutathione, an important antioxidant produced by the body, while quercetin, curcumin, and resveratrol provide complementary antioxidant support. Together, these nutrients help support cellular antioxidant defenses and a healthy inflammatory response.*
  • Each ingredient was selected intentionally, with premium branded forms and nutrient levels informed by published research.

Who This Is For

Designed for women who want more targeted daily support.

  • Women with higher nutritional demands who want to support a healthy inflammatory response and the body's natural antioxidant defenses.*
  • Especially suited to women looking for a research-informed formula that brings several complementary nutrients together in one consistent daily routine.*

Directions

  • Take 3 capsules daily, with food.
  • For a complete daily routine, pair EndoBase with EndoOmega. Consistency matters, so we recommend making it part of a routine you can stick with.
Inside the formula

What's inside — and why

The key ingredients, the role they play in the body, and the published research that informed our formulation.

NAC

N-Acetyl-L-Cysteine

Why we included it

NAC is a precursor to glutathione, one of the body’s key antioxidants. We included it to support the body’s natural antioxidant defenses and help protect cells from oxidative stress.*

Our formula
600 mg
per daily serving

Published research

Selected published research relevant to this ingredient and its nutritional role.

1
Pittaluga E., et al. 2010: More than antioxidant: N-acetyl-L-cysteine in a murine model of endometriosis. Fertil Steril. View study
2
Porpora M.G., et al., 2013: A promise in the treatment of endometriosis: an observational cohort study on ovarian endometrioma reduction by N-acetylcysteine. Evidence-Based Complementary and Alternative Medicine. View study
3
Anastasi E., et al., 2023: Efficacy of N-Acetylcysteine on Endometriosis-Related Pain, Size Reduction of Ovarian Endometriomas, and Fertility Outcomes. International Journal of Environmental Research and Public Health View study

Resveratrol

Japanese Knotweed Root Extract (Polygonum cuspidatum)

Why we included it

Resveratrol is a naturally occurring polyphenol with antioxidant properties. We use Resvenox®, a standardized Japanese knotweed extract providing 30 mg of trans-resveratrol to support antioxidant defenses and cellular health.*

Our formula
30 mg
per daily serving

Published research

Selected published research relevant to this ingredient and its nutritional role.

1
Dull A.M., et al., 2019: Therapeutic Approaches of Resveratrol on Endometriosis via Anti-Inflammatory and Anti-Angiogenic Pathways. Molecules View study
2
Maia H. Jr., et al., 2012: Advantages of the association of resveratrol with oral contraceptives for management of endometriosis-related pain. International Journal of Women’s Health. View study
3
Haghighatdoost F., et al., 2019: Can resveratrol supplement change inflammatory mediators? A systematic review and meta-analysis on randomized clinical trials. European Journal of Clinical Nutrition. View study

Curcumin

Curcumin C3 Reduct® -Curcuma longa extract

Why we included it

Tetrahydrocurcuminoids are metabolites of curcumin with antioxidant activity. We use Curcumin C3 Reduct® to provide a standardized source of tetrahydrocurcuminoids (133mg) that supports antioxidant defenses and a healthy inflammatory response.*

Our formula
140 mg
per daily serving

Published research

Selected published research relevant to this ingredient and its nutritional role.

1
Arablou T., et al., 2018: Curcumin and endometriosis: Review on potential roles and molecular mechanisms. Biomedicine & Pharmacotherapy. View study
2
Vallée A., et al., 2020: Curcumin and Endometriosis. International Journal of Molecular Sciences. View study
3
Zhang Y., et al., 2013: Curcumin inhibits endometriosis endometrial cells by reducing estradiol production. Iranian Journal of Reproductive Medicine. View study

Quercetin

Japanese Pagoda Tree Flower Bud Extract (Sophora japonica)

Why we included it

Quercetin is a naturally occurring plant flavonoid with antioxidant properties. We included a Japanese pagoda tree extract providing quercetin (240 mg) to support antioxidant defenses and a healthy inflammatory response.*

Our formula
252 mg
per daily serving

Published research

Selected published research relevant to this ingredient and its nutritional role.

1
M., et al., 2020: Effectiveness of the integration of quercetin, turmeric, and N-acetylcysteine in reducing inflammation and pain associated with endometriosis. In-vitro and in-vivo studies. Minerva Ginecologica. View study
2
Hipólito-Reis M., et al., 2022: Impact of curcumin, quercetin, or resveratrol on the pathophysiology of endometriosis: A systematic review. Phytotherapy Research. View study

Molybdenum

Why we included it

Molybdenum is an essential trace mineral that acts as a cofactor for enzymes involved in normal sulfur amino acid metabolism. We included it to complement the broader nutrient profile of EndoBase.*

Our formula
150 mcg
per daily serving

Published research

Selected published research relevant to this ingredient and its nutritional role.

1
Pokorska-Niewiada K., et al., 2025: The Role of Antioxidant Minerals in the Pathophysiology and Treatment of Endometriosis—Systematic Review. Antioxidants. View study

Active Folate

Quatrefolic® (6S)-5-methyltetrahydrofolate glucosamine salt

Why we included it

Folate is an essential B vitamin involved in normal cell division and methylation. We use Quatrefolic®, a premium form of 5-MTHF, to provide folate (400 mcg) in its biologically active form.*

Our formula
680 mcg DFE
per daily serving

Published research

Selected published research relevant to this ingredient and its nutritional role.

1
Mikkelsen K., et al., 2019: Vitamin B12, Folic Acid, and the Immune System. Nutrition and Immunity. View study
2
Antoniades C., et al., 2006: 5-methyltetrahydrofolate rapidly improves endothelial function and decreases superoxide production in human vessels: effects on vascular tetrahydrobiopterin availability and endothelial nitric oxide synthase coupling. Circulation. View study
3
Martínez-Garza L.E., 2016: Twenty-five years of knowledge of the prevention of neural tube defects with folic acid. Medicina Universitaria. View study
Ingredient Quality

Not all ingredients are created equal.

What’s on the label is only part of the story. We use premium branded ingredients from established manufacturers, selected for their quality, consistency, and documented specifications.

These branded ingredient technologies give us greater visibility into how an ingredient is sourced, produced, and standardized—so we know more about what goes into every serving.

Curcumin C3 Reduct®

Specialized curcumin technology

Curcumin C3 Reduct® is a branded form of tetrahydrocurcuminoids—the major metabolites of curcumin. We selected it as a premium, standardized source that provides a defined amount of tetrahydrocurcuminoids in every daily serving.

Resvenox®

Standardized trans-resveratrol

Resvenox® is a branded Japanese knotweed root extract standardized to provide trans-resveratrol. We chose it for its defined composition and consistent delivery of the active compound we formulated around.

Quatrefolic®

Active folate as 5-MTHF

Quatrefolic® is a premium form of folate as (6S)-5-methyltetrahydrofolate glucosamine salt. Unlike folic acid, 5-MTHF is already in a biologically active form that can be used directly by the body.*

EndoBase antioxidant and nutrient supplement bottle by EndoMe

EndoBase — Daily Antioxidant + Nutrient Formula

Regular price
$89.00
Regular price
Sale price
$89.00